Primary antibodies conjugated to gold nanoparticles bind directly to the analyte of interest.
Primary gold conjugates
Nano Flow™ primary gold conjugates are ready-to-use reagents designed to directly recognize diagnostic targets such as infectious agents, cardiac biomarkers, inflammatory markers, and more. Produced with highly spherical 40 nm gold nanoparticles at OD20 and under strict quality control, these conjugates provide developers with robust, reproducible tools to accelerate assay prototyping, streamline development, and move seamlessly into manufacturing.
Why choose Nano Flow primary conjugates?
When to use primary conjugates?
During assay prototyping
Rapidly test different targets and assay formats without needing in-house conjugation.
In assay development
As reliable reagents that accelerate screening and optimization phases.
For validated diagnostic targets
As robust detection reagents for infectious disease, cardiac, inflammation, and antimicrobial resistance assays.
For manufacturing scale-up
Same quality from small R&D lots to large-scale production ensures a smooth transition into industrial manufacturing.
Primary vs Secondary conjugates – what’s the difference?
| Primary conjugates | Secondary conjugates |
|---|---|
| Antibody conjugates that bind directly to the target analyte (e.g., CRP, Troponin, Influenza, SARS-CoV-2). | Antibody or protein conjugates that bind to another antibody (e.g., anti-human IgG, anti-mouse IgG, Streptavidin, Protein A/G). |
| Used both in assay development/prototyping and in the final diagnostic assay as the detection reagent. | Used both for assay development (universal detection tools) and in final diagnostic products where secondary detection is the preferred format. |
| Application-specific, tailored to infectious diseases, cardiac, inflammation, antimicrobial resistance, etc. | Flexible reagents with broad applicability across research, prototyping, and commercial LFA manufacturing. |
Portfolio of primary conjugates
| Infectious diseases | Cardiac markers | Inflammatory markers | Antimicrobial resistance | Other targets |
|---|---|---|---|---|
| Zika (anti-E) | BNP | CRP | Anti-KPC mAb | Monkeypox |
| Dengue (anti-NS1) | NT-proBNP (AA 13–27, 27–31, 39–76) | Procalcitonin | Anti-NDM mAb | Influenza-Flu A |
| Chikungunya (anti-E) | — | — | Anti-OXA-48 mAb | Influenza- Flu B |
| West Nile Virus (NS1) | — | — | Anti-VIM mAb | — |
| Malaria (HRP2) | — | — | Anti-IMP mAb | — |
| SARS-CoV-2 (Nucleocapsid) | — | — | — | — |
| Ebola (Glycoprotein) | — | — | — | — |
All Nano Flow primary conjugates are supplied with a Certificate of Analysis, including TEM, DLS, and UV-Vis spectroscopy data, ensuring quality and reproducibility across batches.
